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Drug Patch

Drug patch refers to the raw materials of drugs and suitable materials made for the application in the skin, can produce systemic or local effects of a sheet-like flexible preparations.

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Experimental parameters


Dissolution apparatusRT612-ST  12 Positions Automated Dissolution tester
MethodUSP <724> DRUG RELEASE: Apparatus 6 (Cylinder)
Temperature37℃ ± 0.5℃
Speed50 RPM


①Reproducibility: The RSD range of Sample 1 was 0.63~2.85% while Sample 2 was 1.35~2.99%.

②Distinguish: Under this dissolution method, there is a significant difference between Sample 1 and Sample 2 in terms of in vitro release behavior. It indicates that the method has good discrimination between Sample 1 and Sample 2

CONCLUSION: The RT612-ST provides good reproducibility and discrimination for in vitro performance testing of patches.