Drug Patch
Drug patch refers to the raw materials of drugs and suitable materials made for the application in the skin, can produce systemic or local effects of a sheet-like flexible preparations.
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Experimental parameters
| Dissolution apparatus | RT6 Series Automated Dissolution System |
| Method | USP <724> DRUG RELEASE: Apparatus 6 (Cylinder) |
| Temperature | 37℃ ± 0.5℃ |
| Speed | 50 RPM |
①Reproducibility: The RSD range of Sample 1 was 0.63~2.85% while Sample 2 was 1.35~2.99%.
②Distinguish: Under this dissolution method, there is a significant difference between Sample 1 and Sample 2 in terms of in vitro release behavior. It indicates that the method has good discrimination between Sample 1 and Sample 2
CONCLUSION: The RT6 Series Automated Dissolution System provides good reproducibility and discrimination for in vitro performance testing of patches.
RT614-ST Automated Dissolution System
- Accurate Sampling
- Pipeline System
- Automatic Online Filtering
- Automatic Sample Collection
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RT600 Dissolution Apparatus
- Covered Dissolving Cups
- Convenient Sampling
- Automatic Synchronous Dosing
- Infinite Data Storage
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RT600-ST Automated Dissolution System
- High Anti-adsorption Pipeline
- High-precision Sampling
- Complete Filtration Solutions
- Optional Online Dilution
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RT612 Dissolution Apparatus
- Individual Temperature Monitoring
- Real-time Monitoring of Vital Parameters
- Intelligent Dosing Device
- Optional Dual Drive
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RT612-ST Automated Dissolution System
- High-pressure Resistant Pipeline
- Anti-corrosive Injection Needles
- Flexible Sampling Parameterization
- Optional Dual Drive
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RT600-UV Online UV Dissolution System
- Various pathlengths Support:Supports various flow cells with pathlengths from 1 to 10 mm
- Prevent cross-contamination:Individual flow cells and lines for each dissolution vessel prevent cross-contamination
- Dissolution analysis software: UV dissolution analysis software uses a multi-cell platform to generate accurate and stable data for various samples and methods
- Regulatory complexity: Software supports all regulatory requirements of 21 CFR Part 11
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