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NCE DP6 In-situ Fiber Optic spectrometer

The NCE DP6 in-situ fiber spectrometer combines a deuterium light source with a photodiode array detector to capture key insights into drug dissolution in real time with in-situ fiber technology.

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  • The sampling interval can be flexibly modified
  • Eliminates Complex Pretreatment
  • Supports up to 6 channels of optical fiber synchronous operation
  • Automated Reporting
  • Description

Features

The sampling interval can be flexibly modified

The dissolution dynamics in the medium can be accurately captured within 5 seconds for fast-release samples, which can reflect the drug release behavior in real time.

Eliminates Complex Pretreatment

Measures concentration directly in the analytical medium, enabling fully automated, 24-hour unattended operation.

Supports up to 6 channels of optical fiber synchronous operation

Significantly enhancing analysis efficiency and ensuring data consistency and comparability.

Automated Reporting

The integrated software automatically generates detailed reports upon experiment completion, intuitively visualizing how formulations impact the dissolution, solubility, and permeability of the Active Pharmaceutical Ingredient (API).

Application

Drugs have complex dissolution and permeation behaviors in the body, so the impact of the in vivo environment on the drug needs to be considered during the early drug development or prescription modification process. For this purpose, it is necessary to construct an in vitro environment that can simulate the in vivo environment for experimental research.

  • Intrinsic Dissolution Rate Test

  • PH Shift Model

  • Permeation Model

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Specifications

Product Brochure

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NCE DP6 In-situ Fiber Optic spectrometer


Wavelength range :200-600nm

Wavelength accuracy: ± 1nm

Deuterium lamp life :>1000 hours

Absorbance range: Up to 2AU

Baseline flatness :≤0.002AU

Minimum sampling interval :2 seconds

Noise ≤ 0.002 AU(under 600nm conditions)

Fiber channel :6

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