RT600-ST Automated Dissolution System
The RT600 is an 8-positions, single drive, autosampling dissolution system. It fully meets the testing requirements in Chp (0931), USP (711/724), EP (2.9.3/4). It supports automatic dosing, automatic positioning, automatic sampling, online dilution (optional), and real-time display of speed and temperature. Meeting the needs of high-precision and high-efficiency dissolution testing.
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- High Anti-adsorption Pipeline
- High-precision Sampling
- Complete Filtration Solutions
- Optional Online Dilution
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The device follows USP<1724> specifications to perform in vitro release tests and permeation studies that evaluate creams gels and patches. The instrument design includes a filling point that prevents bubbles from forming which leads to precise and dependable outcomes.
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The RT600-ST performs automatic preheating functions and incorporates covered dissolving cups that maintain uniform testing conditions. Switching methods with this instrument becomes possible because of its paddle-basket co-axial design that requires no recalibration.
The automatic sample collection system has enhanced efficiency by designing a capacity to handle 120 vials in liquid phase format. Continuous filtration occurs through dual online filters that stop equipment clogs from forming.
Features
Automatic preheating
With the automatic preheating function of medium, the instrument can be set to automatically start constant temperature water bath heating at the specified time.
Covered Dissolving Cups
Dissolving cups are automatically centered for fast and accurate installation and greater durability.
Paddle basket co-axial design
Suitable for all kinds of regulations included in the test method. Not necessary to readjust the height of dissolution unit after switching dissolution method.
Automatic Synchronous Dosing
Eliminate the time difference of dosing and the time of dosing can be tracked.
Precise sampling
High-precision sampling pump which can effectively provide accurate and precise sampling.
Pipeline System
Teflon pipeline system with high chemical stability and high anti-adsorption was used to avoid corrosion of sampling pipeline or sample adsorption.
Automatic Online Filtering
Dual on-line filters can be installed, and the instrument can automatically realize the function of embellish washing saturated filter.
Automatic Sample Collection
Comes with a 120-position sample tray for 1.5mL liquid phase vials and a 10mL test tube rack.
Innovative Design
Support for changing solvent volume and stirring speed during the dissolution process
Data Cloud System
Raytor cloud system can connect at least 250 different types of experimental instruments at the same time to realize intelligent management.
Application
Basket and paddle methods are the most commonly used legal dissolution methods in national pharmacopoeias and were the first dissolution methods introduced into pharmacopoeias. They are mainly used for quality control (QC) of pharmaceutical products.
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Oral Tablets
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Patch
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semi-solid preparations
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Injection
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Intrinsic Dissolution Rate of API
Specifications
Product Brochure
General Dissolution System
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Length ×Width× Height(Fully Raised): 63 cm × 56cm ×96 cm |
Dissolution Vessel Number: 8 |
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Setting Range: 20-250 rpm (RPM) |
RPM Resolution: 0.01RPM |
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Steady Speed Error: ≤±0.3RPM |
Temp. Accuracy: ≤±0.2℃ |
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Temp. Resolution: 0.01 ℃ |
Level: ＜ 0.5° |
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Vessel Verticality: 90°±0.5° |
Shaft Verticality: 90°±0.5° |
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Centering Deviation: ＜ ±2.0 mm |
Depth Positioning Deviation: ＜ ±1.0 mm |
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Shaft Wobble: ＜ ±1.0 mm |
Basket Wobble: ＜ ±1.0 mm |
Automatic Sampling Workstation
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Length ×Width× Height: 40 cm ×70cm ×70 cm |
Maximum Settable Sample Number: 20 |
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Sampling Range: 1 ~ 20ml |
Minimum Sampling Interval: First Sampling Point: 3 minutes |
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Maximum Working Time: 720 hours |
Sampling Precision: ≤±1% |
Operating System
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Meeting FDA21 CFR Part 11 |
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